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Role of metallothionein-III following central nervous system damage

✍ Scribed by Javier Carrasco; Milena Penkowa; Mercedes Giralt; Jordi Camats; Amalia Molinero; Iain L. Campbell; Richard D. Palmiter; Juan Hidalgo

Book ID
117688497
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
983 KB
Volume
13
Category
Article
ISSN
0969-9961

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## Abstract We examined metallothionein (MT)‐induced neuroprotection during kainic acid (KA)‐induced excitotoxicity by studying transgenic mice with MT‐I overexpression (TgMT mice). KA induces epileptic seizures and hippocampal excitotoxicity, followed by inflammation and delayed brain damage. We s