Role of Smad2/3 and p38 MAP kinase in TG
✍
Irina Kolosova; David Nethery; Jeffrey A. Kern
📂
Article
📅
2011
🏛
John Wiley and Sons
🌐
English
⚖ 351 KB
👁 1 views
## Abstract Idiopathic pulmonary fibrosis is characterized by myofibroblast accumulation, extracellular matrix (ECM) remodeling, and excessive collagen deposition. ECM‐producing myofibroblasts may originate from epithelial cells through epithelial to mesenchymal transition (EMT). TGF‐β1 is an induc