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Role of Kupffer cells in failure of fatty livers following liver transplantation and alcoholic liver injury

โœ Scribed by RONALD G THURMAN; WENSHI GAO; HENRY D CONNOR; YUKITO ADACHI; ROBERT F STACHLEWITZ; ZHI ZHONG; KATHRYN T KNECHT; BLAIR U BRADFORD; RONALD P MASON; JOHN J LEMASTERS

Book ID
115170798
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
595 KB
Volume
10
Category
Article
ISSN
0815-9319

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It is well recognized that consumption of alcohol leads to liver disease in a dose-dependent manner; however, the exact mechanisms remain unclear. Hypoxia subsequent to a hypermetabolic state may be involved: therefore, when it was observed recently that inactivation of Kupffer cells prevented stimu