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Role of intracellular reactive oxygen species and mitochondrial dysfunction in evening primrose extract-induced apoptosis in Ehrlich ascites tumor cells

✍ Scribed by Tsutomu Arimura; Akiko Kojima-Yuasa; Sanae Watanabe; Mayu Suzuki; David Opare Kennedy; Isao Matsui-Yuasa

Book ID: 114009024
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 710 KB
Volume: 145
Category: Article
ISSN: 0009-2797
DOI: 10.1016/s0009-2797(03)00060-7

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## Abstract Screening of various natural products in a search for novel inducers of apoptosis in human leukemia cells led us to identify the strong apoptosis‐inducing activity in a fraction extracted with methanol from the roots of __Sophora subprostrata__ Chun et T. Chen. We purified the compound