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Role of interferon alpha-2b, chlorambucil and prednisone in the treatment of chronic lymphocytic leukemia

✍ Scribed by Dr. Stefano Molica


Book ID
114791568
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
183 KB
Volume
48
Category
Article
ISSN
0902-4441

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Ninety-six patients with advanced chronic lymphocytic leukemia (CLL) (Stage C; anemia and/or thrombocytopenia of nonimmune origin) were randomized to receive either chlorambucil (CLR) (0.4 mg/kg orally, day 6) plus prednime (PDN) (60 mg/m2 orally, days 1-5) every 2 weeks or cyclophosphamide (600 mg/

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Studies of the effect of interferon on the growth of colonies of myeloid leukemic blasts, myeloma colony-forming cells and normal hemopoietic precursor cells have shown that interferon does not specifically inhibit the growth of the malignant cells in culture, i.e. the growth of the malignant and th