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Role of IL-6 and Its Soluble Receptor in Induction of Chemokines and Leukocyte Recruitment

✍ Scribed by Maria Romano; Marina Sironi; Carlo Toniatti; Nadia Polentarutti; Paolo Fruscella; Pietro Ghezzi; Raffaella Faggioni; Walter Luini; Victor van Hinsbergh; Silvano Sozzani; Federico Bussolino; Valeria Poli; Gennaro Ciliberto; Alberto Mantovani


Book ID
117722715
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
206 KB
Volume
6
Category
Article
ISSN
1074-7613

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Increasing evidence supports an essential role for interleukin-6 (IL-6) in the development, differentiation, as well as de-and re-generation of neurons in the central nervous system (CNS). Both IL-6 and its specific receptor (IL-6R) are expressed on neurons and glial cells including astrocytes. In t