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Role of IL-28B and inosine triphosphatase polymorphisms in efficacy and safety of Peg-Interferon and ribavirin in chronic hepatitis C compensated cirrhosis with and without oesophageal varices

✍ Scribed by V. Di Marco; V. Calvaruso; S. Grimaudo; D. Ferraro; R. M. Pipitone; R. Di Stefano; A. Craxì


Book ID
119836607
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
215 KB
Volume
20
Category
Article
ISSN
1352-0504

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Chronic hepatitis C virus (HCV) infection is usually asymptomatic in children, but significant liver disease may occur. We evaluated the efficacy, safety, and pharmacokinetics of interferon alfa-2b and ribavirin in children with chronic HCV. We determined the optimal ribavirin dose in an initial coh