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Role of idiotype–anti-idiotype interactions in the induction of collagen-induced arthritis in rats

✍ Scribed by Liubov Beduleva; Igor Menshikov

Book ID
116569476
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
713 KB
Volume
215
Category
Article
ISSN
0171-2985

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Idiotype-anti-idiotype interactions and
Idiotype-anti-idiotype interactions and the control of the anti-β(2→6) polyfructosan response in the mouse: specificity and idiotypy of anti-ABPC48 anti-idiotypic monoclonal antibodies
✍ Pierre Legrain; Danielle Voegtle; Gérard Buttin; Pierre André Cazenave 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 936 KB

## Abstract Seventeen hybridomas, secreting monoclonal anti‐idiotypic antibodies (IDA) directed against the BALB/c ABPC48 idiotype, were isolated from one immunized BALB/c mouse. Several IDA also bind another BALB/c idiotype: UPC10. ABPC48 and UPC10 are both myeloma proteins with a β(2→6)‐polyfruct