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Role of hypoxia and EGF on expression, activity, localization and phosphorylation of carbonic anhydrase IX in MDA-MB-231 breast cancer cells

✍ Scribed by Ying Li; Hai Wang; Chingkuang Tu; Kathleen T. Shiverick; David N. Silverman; Susan C. Frost


Book ID
113486411
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
722 KB
Volume
1813
Category
Article
ISSN
0167-4889

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## Abstract External (but not internal) application of β‐estradiol (E2) increased the current amplitude of voltage‐gated Na^+^ channels (VGSCs) in MDA‐MB‐231 human breast cancer (BCa) cells. The G‐protein activator GTP‐γ‐S, by itself, also increased the VGSC current whilst the G‐protein inhibitor G