Role of humoral immune responses in hepatitis B and C virus infections
β Scribed by M. U. MONDELLI; A. CIVIDINI; A. CERINO
- Book ID
- 114727478
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 562 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0014-2972
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Immunoglobulin GM and KM allotypes-genetic markers of β₯ and chains, respectively-are associated with immune responsiveness to several infectious pathogens and with survival in certain viral epidemics. We hypothesized that GM and KM allotypes affect the outcome of hepatitis C virus (HCV) infection. T
Several lines of evidence have suggested that immune mechanisms are involved in the pathogenesis of hepatitis B virus (HBV)-and hepatitis C virus (HCV)-related hepatitis. Study of patients with dual HBV and HCV infection raises the question of which is etiologically more relevant in determining the