Role of human transcription elongation factor DSIF in the suppression of senescence and apoptosis
โ Scribed by Toshiharu Komori; Naoto Inukai; Tomoko Yamada; Yuki Yamaguchi; Hiroshi Handa
- Book ID
- 108732081
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 463 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1356-9597
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## Abstract **Background:** The human Spt4/Spt5 complex, termed DRBโsensitivity inducing factor (DSIF) is a dual regulator of transcription that stimulates, or, when cooperating with negative elongation factor (NELF), represses RNA polymerase II (RNAPII) elongation. Spt4 and Spt5 are also thought t