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Role of human papillomavirus and cell cycle-related variants in squamous cell carcinoma of the oropharynx

✍ Scribed by Guojun Li; Zhigang Huang; Xingming Chen; Qingyi Wei

Book ID
117802877
Publisher
Journal of Biomedical Research
Year
2010
Tongue
English
Weight
546 KB
Volume
24
Category
Article
ISSN
1674-8301

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## Abstract ## BACKGROUND. Tobacco smoking, alcohol abuse, and high‐risk human papillomavirus (HPV) are risk factors in the etiology of oropharyngeal squamous cell carcinomas (SCCs). The __TP53__ polymorphism, in which an arginine (R) is changed to proline (P) at codon 72, is functionally signific