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Role of histone acetylation in the control of gene expression

✍ Scribed by Verdone, Loredana; Caserta, Micaela; Mauro, Ernesto Di

Book ID: 120596246
Publisher: NRC Research Press
Year: 2005
Tongue: English
Weight: 362 KB
Volume: 83
Category: Article
ISSN: 0829-8211
DOI: 10.1139/o05-041

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Increasing evidence from recent research suggests a connection between cancer and a deranged equilibrium of histone acetylation, which is maintained by two competing enzymatic activities, histone acetyltransferases (HATs) and histone deacetylases (HDACs). It is our hypothesis that a significant prop