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Role of His(E7) in Regulating Ligand Binding to the Subunits of Human HbA

✍ Scribed by Birukou, Ivan; Schweers, Rachel L.; Olson, John S.


Book ID
123281938
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
45 KB
Volume
98
Category
Article
ISSN
0006-3495

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## Abstract The I domain of integrin Ξ±E was modeled on the crystal structure of that in CD11b and mutated to produce an open (high affinity) or closed (low affinity) conformation. K562 transfectants expressing mutant Ξ±E and wild‐type Ξ²7 were tested for adhesion to E‐cadherin‐Fc. Downward displaceme