Role of Helicobacter pylori infection in aberrant DNA methylation along multistep gastric carcinogenesis
โ Scribed by Cheol Min Shin; Nayoung Kim; Younmu Jung; Ji Hyun Park; Gyeong Hoon Kang; Joo Sung Kim; Hyun Chae Jung; In Sung Song
- Book ID
- 108586701
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 395 KB
- Volume
- 101
- Category
- Article
- ISSN
- 1347-9032
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## Background: Gastric cancer is the most frequently diagnosed malignancy in japan. the possible relationship between helicobacter pylori infection and gastric cancer in japan was evaluated. ## Methods: H. pylori infection was identified by the presence of anti-h. pylori igg. the frequency of h.
## Abstract Aberrant DNA methylation is deeply involved in human cancers, but its inducers and targets are still mostly unclear. __Helicobacter pylori__ infection was recently shown to induce aberrant methylation in gastric mucosae, and produce a predisposed field for cancerization. Here, we analyz