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Role of GTPases in ribosome assembly

✍ Scribed by Katrin Karbstein

Publisher
Wiley (John Wiley & Sons)
Year
2007
Tongue
English
Weight
278 KB
Volume
87
Category
Article
ISSN
0006-3525

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✦ Synopsis

Abstract

GTPases are a universally conserved class of regulatory proteins involved in such diverse cellular functions as signal transduction, translation, cytoskeleton formation, and intracellular transport. GTPases are also required for ribosome assembly in eukaryotes and bacteria, where they present themselves as possible regulatory molecules. Strikingly, in bacteria they represent the largest class of essential assembly factors. A review of their common structural, biochemical and genetic interactions is presented and integrated with models for their function in ribosome assembly. Β© 2007 Wiley Periodicals, Inc. Biopolymers 87: 1–11, 2007

This article was originally published online as an accepted preprint. The β€œPublished Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at [email protected]

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