Role of glutathione in the induction of apoptosis and c-fos and c-jun mRNAs by oxidative stress in tumor cells
✍ Scribed by Carmen Tormos; F Javier Chaves; Maria José Garcia; Federico Garrido; Ramiro Jover; José Enrique O'Connor; Antonio Iradi; Ana Oltra; Maria R Oliva; Guillermo T Sáez
- Book ID
- 116332973
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 327 KB
- Volume
- 208
- Category
- Article
- ISSN
- 0304-3835
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The proto-oncogenes c-fos and c-jun have been shown in numerous model systems to be induced within minutes of growth factor stimulation, during the Go/G1 transition. In this report we use the mitotic shake-off procedure to generate a population of highly synchronized Swiss 3T3 cells. We show that bo
## Abstract The AP1 transcriptional complex is a heterodimer composed of proteins encoded by the fos and jun proto‐oncogene families. Changes in the concentration and composition of AP1 occur after cells are perturbed in a variety of different ways (Curran, in Reddy et al., eds. “The Oncogene Handb