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Role of glutathione in reduction of arsenate and of γ-glutamyltranspeptidase in disposition of arsenite in rats

✍ Scribed by Iván Csanaky; Zoltán Gregus

Book ID
108287155
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
215 KB
Volume
207
Category
Article
ISSN
0300-483X

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The role of extracellular glutathione (GSH) and membrane-bound y-glutamyltranspeptidase (yGT) as contributory factors in the disposition and toxicity of inorganic mercury (HgCI2, 1 mg kg-', i.p.) was investigated in rats pretreated with acivicin (AT-125, 10 mg kg-I), a y-GT inhibitor. A high degree