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Role of Gln 85 of human CYP27A1 in 25-hydroxyvitamin D3-binding and protein folding

โœ Scribed by Natsumi Sawada; Keiko Yamamoto; Sachiko Yamada; Shinichi Ikushiro; Masaki Kamakura; Miho Ohta; Kuniyo Inouye; Toshiyuki Sakaki

Book ID
116294414
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
694 KB
Volume
355
Category
Article
ISSN
0006-291X

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1,25-Dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ] has many noncalcemic actions that rest on inhibition of proliferation and promotion of differentiation in malignant and normal cell types. 1,25(OH) 2 D 3 stimulates osteoblast differentiation of human marrow stromal cells (hMSCs), but little is known about