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Role of glial cell derived neurotrophic factor in the protective effect of smilagenin on rat mesencephalic dopaminergic neurons damaged by MPP+

✍ Scribed by Yongfang Zhang; Zongqin Xia; Yaer Hu; Antonia Orsi; Daryl Rees


Book ID
113620652
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
404 KB
Volume
582
Category
Article
ISSN
0014-5793

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Parkinson's disease is characterized by the progressive degeneration of midbrain dopaminergic neurons. Several studies have examined the effects of the dopaminergic neurotrophins growth/differentiation factor 5 (GDF5) and glial cell line-derived neurotrophic factor (GDNF) on these neurons in vitro.