Specificity and sensitivity of hexosamin
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Maria J. G. Fernandes; Feige Kaplan; Caroline L. Clow; Peter Hechtman; Charles R
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Article
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1992
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John Wiley and Sons
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English
β 455 KB
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Tay-Sachs disease (TSD), a neurodegenerative disorder resulting from a deficiency of the lysosomal enzyme hexosaminidase A (HexA), clusters in Ashkenazic Jews. Population-based screening programs to detect carriers of TSD genes by means of HexA assays have been active since the 1970s. The recent cha