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Role of Gadd45α in the density-dependent G1 arrest induced by p27Kip1

✍ Scribed by Zhang, Xiaohong; Ma, Le; Enkemann, Steven A; Pledger, W J


Book ID
110067696
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
203 KB
Volume
22
Category
Article
ISSN
0950-9232

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Our previous study demonstrate that vitamin D 3 induces the binding of vitamin D 3 receptor (VDR) to Sp1 transcription factor and stimulates p27 Kip1 expression via the Sp1 consensus sequences in the promoter. Both VDR and Sp1 are transcriptional activators, it is unclear which protein functions as