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Role of estradiol and 2-hydroxyestradiol in melanin formation in vitro

✍ Scribed by Jacobsohn, Gert M.; Chiartas, Pamela L.; Hearing, Vincent J.; Jacobsohn, Myra K.

Book ID
123195806
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
698 KB
Volume
966
Category
Article
ISSN
0304-4165

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## Abstract An elevated incidence of breast cancer in women has been associated with prolonged exposure to high levels of estrogens. Our laboratory demonstrated that treatment of the immortalized human breast epithelial cells MCF‐10F with 17β‐estradiol (E~2~), 4‐hydroxyestradiol (4‐OHE~2~) or 2‐hyd