Role of enterovirus infections in IgE sensitization
✍ Scribed by Tapio Seiskari; Anita Kondrashova; Sisko Tauriainen; Mikael Knip; Hanna Viskari; Anna-Maija Haapala; Heikki Hyöty
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 73 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0146-6615
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Among other infectious agents, enteroviruses have been associated with protection against allergic diseases. The aim of the present study was to confirm these findings using a highly sensitive and specific neutralization antibody assay and to investigate whether the protective effect is related to certain enterovirus serotypes. Antibodies against 12 enterovirus serotypes were measured in 60 children who were positive for allergen‐specific IgE and in 190 control children. Echoviruses seemed to be more protective than coxsackie‐B‐viruses and echovirus 11 had the strongest independent protective effect (P = 0.001; OR = 0.35, 95% CI: 0.18–0.67). The results support previous observations suggesting that infections by certain enterovirus types are associated with protection against IgE sensitization. J. Med. Virol. 84:268–271, 2012. © 2011 Wiley Periodicals, Inc.
📜 SIMILAR VOLUMES
Data are presented of IgM detection by a neutralization test used routinely in 1,062 patients. Antigens isolated during the period of investigation were EV4, EV7, EV11, EV18, EV21, EV24, EV33, CA9, CB2, CB4, and CB5. No difference was observed in the distribution of IgM-positive sera according to ag
Data have been gathered and collated from a variety of sources both published and unpublished, dealing with the concentration of enteroviruses in human stools. For polioviruses, a general range of 3.0-6.5 log10 TCD50 per gram of stool was reported, whereas for coxsackieviruses and echoviruses the ra
Enterovirus infections may initiate and accelerate the beta-cell damaging process leading to Type 1 (insulin-dependent) diabetes mellitus (Type 1 DM). Recent prospective studies have suggested that this can happen long before overt disease and even in utero. We describe an infant, followed regularly
## Abstract The epidemiological, virological, and clinical data of 119 infants less than 30 days of age with enteroviral infection collected from January 1993 to November 1995 by the diagnostic virology laboratories were analyzed retrospectively. Ninety‐eight isolates (83%) were obtained in the per