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Role of endotoxin in the hepatic microvascular inflammatory response to ethanol

โœ Scribed by RS MCCUSKEY; J NISHIDA; H EGUCHI; D MCDONNELL; GL BAKER; W EKATAKSIN; MA KRASOVICH; V RUDI; HK SEITZ; B URBASCHEK; R URBASCHEK

Book ID
115170797
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
761 KB
Volume
10
Category
Article
ISSN
0815-9319

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Chylomicrons alter the hepatic distribut
Chylomicrons alter the hepatic distribution and cellular response to endotoxin in rats
โœ Hobart W. Harris; Don C. Rockey; Phuonglan Chau ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 192 KB

## Chylomicrons (CM) can bind endotoxin (lipopolysaccharide [LPS] ), forming CM-LPS complexes, and protect against endotoxic shock and death in rodent models of gramnegative sepsis. The liver appears to play a central role in this process, as demonstrated by the increased uptake of LPS by this org