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Role of endothelin in the development of hemorrhagic pancreatitis in rats

โœ Scribed by Xiao-Hong Liu; Itsuro Nakano; Tetsuhide Ito; Hiroya Yamaguchi; Yoshikatsu Migita; Toshihiko Miyahara; Shujiro Koyanagi; Keiichiro Ohgoshi; Hajime Nawata


Publisher
Springer Japan
Year
1995
Tongue
English
Weight
673 KB
Volume
30
Category
Article
ISSN
0944-1174

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We determined the functional role of nitric oxide (NO) and endothelins (ET), two potent vasoactive mediator systems in the liver, for the pathogenesis of sinusoidal perfusion failure and lethal hepatocyte injury after low-flow ischemia/reperfusion in the isolated perfused rat liver. NO synthase bloc