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Role of endoplasmic reticulum stress in light-induced photoreceptor degeneration in mice

โœ Scribed by Nakanishi, Tomohiro; Shimazawa, Masamitsu; Sugitani, Sou; Kudo, Takashi; Imai, Shunsuke; Inokuchi, Yuta; Tsuruma, Kazuhiro; Hara, Hideaki

Book ID
120137425
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
870 KB
Volume
125
Category
Article
ISSN
0022-3042

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## Abstract Exposure to excessive levels of light induces photoreceptor apoptosis and has previously been used as a model for the study of retinal degeneration. During the light exposure, intracellular calcium levels increase, and reactive oxygen species (ROS) are generated, which have been shown t