Role of ecto-kinase in phorbol ester-enhanced growth hormone-binding protein release from human IM-9 cells

Decreased serum dependence in the growth

Decreased serum dependence in the growth of NIH3T3 cells from the overexpression of human nuclear receptor-binding SET-domain-containing protein 1 (NSD1) or fission yeast su(var)3-9, enhancer-of-zeste, trithorax 2 (SET2)

✍ Toshiko Yamada-Okabe; Naomichi Matsumoto 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 148 KB 👁 2 views

## Abstract Nuclear receptor‐binding SET‐domain‐containing protein 1 (__NSD1__), a culprit gene for Sotos syndrome, contains a su(var)3‐9, enhancer‐of‐zeste, trithorax (SET) domain that is responsible for histone methyltransferase activity and other domains such as plant homeodomain (PHD) and proli