Role of DNA Methylation and Histone Acetylation in Steroid Receptor Expression in Breast Cancer
โ Scribed by Lan Yan; Xiaowei Yang; Nancy E. Davidson
- Book ID
- 110299709
- Publisher
- Springer US
- Year
- 2001
- Tongue
- English
- Weight
- 140 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1083-3021
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๐ SIMILAR VOLUMES
Carcinoma of the breast is a leading hormone-dependent malignancy, resulting in a high rate of morbidity and mortality. During the complex multi-step process of tumor promotion, this common cancer is initiated as hormone-responsive (HR), non-metastatic cancer, followed by a gradual transition into a
## Abstract Mucins are highly glycosylated proteins that play important roles in carcinogenesis. In pancreatic neoplasia, MUC2 mucin has been demonstrated as a tumor suppressor and we have reported that MUC2 is a favorable prognostic factor. Regulation of __MUC2__ gene expression is known to be con