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Role of distinct phospholipases A2 and their modulators in meconium aspiration syndrome in human neonates

✍ Scribed by Daniele De Luca; Angelo Minucci; Domenico Tripodi; Marco Piastra; Domenico Pietrini; Cecilia Zuppi; Giorgio Conti; Virgilio P. Carnielli; Ettore Capoluongo


Publisher
Springer
Year
2011
Tongue
English
Weight
247 KB
Volume
37
Category
Article
ISSN
1432-1238

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The role of Asp-49 and other conserved a
✍ Carel J. van den Bergh; Arend J. Slotboom; Hubertus M. Verheij; Gerard H. de Haa πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 778 KB

The role of aspartic acid49 (Asp-49) in the active site of porcine pancreatic phospholipase A2 was studied by recombinant DNA techniques: two mutant proteins were constructed containing either glutamic acid (Glu) or lysine (Lys) at position 49. Enzymatic characterization indicated that the presence