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Role of detoxifying enzyme polymorphism in susceptibility to alcoholic liver disease

โœ Scribed by A. Hurlstone; Alison M. Brind; Neil Fisher; Richard C. Strange; Anthony A. Fryer

Book ID
119527534
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
129 KB
Volume
34
Category
Article
ISSN
0168-8278

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## Abstract Cancer risk can be influenced by the exposure to endogenous or environmental toxins. Polymorphic enzymes involved in the metabolic activation/detoxification of carcinogens may account for individual variations of risk. We studied the polymorphisms of five enzymes of the P450 superfamily