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Role of defective monocyte interleukin-10 release in tumor necrosis factor—alpha overproduction in alcoholic cirrhosis

✍ Scribed by Olivier Le Moine; Arnaud Marchant; Donat De Groote; Camille Azar; Michel Goldman; Jacques Devière

Book ID
119155935
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
418 KB
Volume
22
Category
Article
ISSN
0270-9139

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Role of defective monocyte interleukin-1
Role of defective monocyte interleukin-10 release in tumor necrosis factor-alpha overproduction in alcoholic cirrhosis
✍ Olivier le Moine; Arnaud Marchant; Donat de Groote; Camille Azar; Michel Goldman 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 478 KB

## Monocytes of patients with alcoholic cirrhosis pro duce higher amounts of tumor necrosis factor-alpha (me) after lipopolysaccharide (LPS) stimulation. The mechanisms of this overproduction remain undefined. IL-10 (IL-10) is an antiinflammatory cytokine known to downregulate TNF-a secretion by m