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Role of Cytosolic Calcium Diffusion and Sarcolemmal T-Type Calcium Current in Triggered Activity in Purkinje Cells: A Simulation Study

✍ Scribed by Deo, M.; Pandit, S.V.; Vaidyanathan, R.; OConnell, R.; Milstein, M.; Musa, H.; Herron, T.; Anumonwo, J.M.; Jalife, J.; Berenfeld, O.

Book ID: 123539975
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 224 KB
Volume: 8
Category: Article
ISSN: 1547-5271
DOI: 10.1016/j.hrthm.2011.09.032

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A combined study of sodium current and T

A combined study of sodium current and T-type calcium current in isolated cardiac cells

✍ J. Tytgat; J. Vereecke; E. Carmeliet 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 699 KB

Sodium currents (INa) and T-type calcium currents (ICa,T) of isolated guinea-pig ventricular myocytes were recorded using the whole-cell voltage-clamp technique. Separation of the two currents was obtained by using the difference current method in the presence and absence of 2 mM extracellular Na (N