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Role of cytochrome P-450 genetic polymorphisms in oral carcinogenesis

✍ Scribed by Miriam Hernando-Rodriguez; Natalia Rey-Barja; Xabier Marichalar-Mendia; Maria J. Rodriguez-Tojo; Amelia Acha-Sagredo; Jose M. Aguirre-Urizar


Book ID
111255529
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
166 KB
Volume
41
Category
Article
ISSN
0904-2512

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Rat colon mucosa microsomes contain a competent mixed function oxidase system that hydroxylates the N-methyl drugs benzphetamine and ethylmorphine, the 0-alkyl drugs p-nitroanisole and p-nitrophenetole and the polycyclic carcinogen benzo[a]pyrene. The colon system's hydroxylation activities can be s