Role of colonic cytochrome P-450 in larg
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Henry W. Strobel; Wan-Fen Fang; R. Joan Oshinsky
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Article
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1980
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John Wiley and Sons
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English
β 611 KB
Rat colon mucosa microsomes contain a competent mixed function oxidase system that hydroxylates the N-methyl drugs benzphetamine and ethylmorphine, the 0-alkyl drugs p-nitroanisole and p-nitrophenetole and the polycyclic carcinogen benzo[a]pyrene. The colon system's hydroxylation activities can be s