The role of the cysteine residue in the
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NagaRekha Pasupuleti; Mahesha Gangadhariah; Smitha Padmanabha; Puttur Santhoshku
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Article
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2010
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John Wiley and Sons
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English
⚖ 416 KB
## Abstract The small heat shock protein Hsp27 is a molecular chaperone and an anti‐apoptotic protein. Human Hsp27 has one cysteine residue at position 137. We investigated the role of this cysteine residue in the chaperone and anti‐apoptotic functions of Hsp27 by mutating the cysteine residue to a