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Role of cysteine residues in the enhancement of chaperone function in methylglyoxal-modified human αA-crystallin

✍ Scribed by Santosh R. Kanade; NagaRekha Pasupuleti; Ram H. Nagaraj


Publisher
Springer
Year
2008
Tongue
English
Weight
450 KB
Volume
322
Category
Article
ISSN
0300-8177

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## Abstract The small heat shock protein Hsp27 is a molecular chaperone and an anti‐apoptotic protein. Human Hsp27 has one cysteine residue at position 137. We investigated the role of this cysteine residue in the chaperone and anti‐apoptotic functions of Hsp27 by mutating the cysteine residue to a