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Role of cyclooxygenase 2, p38 and p42/44 MAPK in the secretion of prostacyclin induced by epidermal growth factor, endothelin-1 and angiotensin II in rat ventricular cardiomyocytes

✍ Scribed by Michela C Rebsamen; Romina Capoccia; Michel B Vallotton; Ursula Lang


Book ID
117141649
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
505 KB
Volume
35
Category
Article
ISSN
0022-2828

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Several agents that act through G-protein-coupled receptors and also stimulate phosphoinositide-specific phospholipase C (PI-PLC), including angiotensin II, vasopressin, norepinephrine, and prostaglandin (PG) F 2a , activated the ERK1 (p44 mapk ) and ERK2 (p42 mapk ) members of the mitogen-activated