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Role of cyclic amp in steroidogenesis in leydig cells: ‘Discrepancies’ between effects of luteinizing hormone and cholera toxin

✍ Scribed by B.A. Cooke; L.M. Lindh; F.H.A. Janszen

Book ID
115907146
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
361 KB
Volume
73
Category
Article
ISSN
0014-5793

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The effect of time-controlled exposures to cholera toxin (CT) on intracellular levels of cyclic AMP (CAMP) and on the proliferative response of serumstimulated 3T3 cells was investigated. Continuous exposure to CT caused up to 8-fold raises in cAMP content and inhibited DNA replication by delaying G