Expression of the wilms' tumor gene WT1
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Anthonie W. Langerak; Kathleen A. Williamson; Kiyoshi Miyagawa; Anne Hagemeijer;
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Article
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1995
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John Wiley and Sons
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English
⚖ 929 KB
Mutations in the WTI tumor suppressor gene are known t o contribute t o the development of Wilms' tumor (WT) and associated gonadal abnormalities. WTI is expressed principally in the fetal kidney, developing gonads, and spleen and also in the mesothelium, which lines the coelomic cavities. These tis