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Role of cholesterol in amyloid cascade: cholesterol-dependent modulation of tau phosphorylation and mitochondrial function

✍ Scribed by M. Michikawa

Book ID
109337469
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
128 KB
Volume
114
Category
Article
ISSN
0001-6314

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## Abstract Recently, we have found that alterations in cellular cholesterol metabolism are involved in promotion of tau phosphorylation (Fan et al. [2001] J. Neurochem. 76: 391–400; Sawamura et al. [2001] J. Biol. Chem. 276:10314–10319). In addition, we have shown that amyloid β‐protein (AΞ²) promo