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Role of CFTR mutations in evolution and severity of chronic pancreatitis

✍ Scribed by Monica Gallo; Ezio Gaia; Claudia Bancone; Paola Salacone; Giovanni Gerbino Promis; Alfredo Brusco; Marina Ferrone; Alberto Angeli; Piana Maria Rita; Carlo Arduino

Book ID
119630009
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
142 KB
Volume
32
Category
Article
ISSN
1590-8658

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Cystic fibrosis is a common, fatal disorder caused by abnormalities in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. CFTR encodes a chloride channel that regulates secretion in many exocrine tissues. The presentation of cystic fibrosis is highly variable as measured by the age