✦ LIBER ✦

Role of cell cholesterol in modulating antineoplastic ether lipid uptake, membrane effects and cytotoxicity

✍ Scribed by Luisa Diomede; Adalgisa Bizzi; Armando Magistrelli; Edward J. Modest; Mario Salmona; Alessandro Noseda

Publisher: John Wiley and Sons
Year: 1990
Tongue: French
Weight: 648 KB
Volume: 46
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910460234

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✦ Synopsis

Publication of the International Union Against Cancer Publication de I'Union lnternationale Contre 18 Cancer

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## Abstract The relationship between cell‐membrane permeability to vincristine and cholesterol/phospholipid levels was studied in L5I7SY murine leukemic lymphoblasts and in 2 multidrug‐resistant cell sublines, VCR/P60 and VCR/P200, which expressed increasing levels of vincristine resistance. The up