Role of CD44 in tumour progression and strategies for targeting
β Scribed by Negi, Lalit Mohan; Talegaonkar, Sushama; Jaggi, Manu; Ahmad, Farhan J.; Iqbal, Zeenat; Khar, Roop K.
- Book ID
- 118057775
- Publisher
- Informa plc
- Year
- 2012
- Tongue
- English
- Weight
- 936 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1061-186X
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CD44 is a widely expressed cell surface glycoprotein with various functions. This molecule is shed from the cell surface and released as a soluble molecule. High serum levels of CD44 have been demonstrated in some solid tumours. In this study we measured serum CD44 in 25 patients with acute leukemia
To clarify the possible role of CD44 expression in ovarian tumour development and progression, an immunohistochemical investigation was undertaken of a series of 115 carcinomas, 32 tumours with low malignant potential (LMP), and 53 cystadenomas. A combination of the reverse transcription-polymerase