Role of cannabinoid CB1 receptors and Gi/o protein activation in the modulation of synaptosomal Na+,K+-ATPase activity by WIN55,212-2 and ▵9-THC

Cannabinoid agonist WIN55,212-2 induces

Cannabinoid agonist WIN55,212-2 induces apoptosis in cerebellar granule cells via activation of the CB1 receptor and downregulation of bcl-xL gene expression

✍ Giacomo Pozzoli; Giuseppe Tringali; Mauro Vairano; Monia D'Amico; Pierluigi Nava 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 319 KB

## Abstract The endogenous cannabinoid system is involved in the regulation of a number of physiologic effects in both the central and peripheral nervous systems. Its role in the control of neuronal cell proliferation has attracted major attention because of its potential implications for new thera