Role of cAMP-Dependent Protein Kinase on Acute Picrotoxin-Induced Seizures
✍ Scribed by Araceli Vázquez-López; Germán Sierra-Paredes; Germán Sierra-Marcuño
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 213 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0364-3190
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The cell line A126-1B2 is a PC12-derived mutant that is resistant to the toxic effects of dibutyryladenosine 3'5'-cyclic monophosphate (dbcAMP) and is deficient in adenosine 3':5'-cyclic monophosphate (CAMP)-dependent protein kinase I1 (PKAII). This mutant formed neurites in response to nerve growth
## Abstract Characterization of the unfolding dynamics of a recombinant type IA regulatory subunit (RIα) of cyclic adenosine monophosphate (cAMP)‐dependent protein kinase (cAPK) was examined by CE with UV detection. Electrophoretic separation of RIα by CE in a buffer devoid of cAMP resulted in rapi