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Role of calcium signaling in the activation of mitochondrial nitric oxide synthase and citric acid cycle

✍ Scribed by Traaseth, Nathaniel; Elfering, Sarah; Solien, Joseph; Haynes, Virginia; Giulivi, Cecilia

Book ID
125426233
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
184 KB
Volume
1658
Category
Article
ISSN
0005-2728

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Nitric oxide synthase (NOS) activity was determined in adult rat frontal cortex and hippocampus by measuring the conversion of L-[3H]arginine to L-[3H]citrulline. N-methyl-D-aspartate (NMDA), but not kainate or a-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA), stimulated NOS activity. This ef