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Role of Calcineurin-Mediated Dephosphorylation in Modulation of an Inwardly Rectifying K+Channel in Human Proximal Tubule Cells

✍ Scribed by Manabu Kubokawa; Toshiyuki Kojo; You Komagiri; Kazuyoshi Nakamura

Publisher
Springer
Year
2009
Tongue
English
Weight
592 KB
Volume
231
Category
Article
ISSN
0022-2631

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✍ Pancrazio, Joseph J. ;Ma, Wu ;Grant, Geraldine M. ;Shaffer, Kara M. ;Kao, Winfre πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 170 KB

The whole-cell patch-clamp technique was used to assess the current carried by inwardly rectifying K Ψ‰ channels (K ir ) and the resting membrane potential (RMP) during long-term culture of NG108-15 cells. Culture of this cell line in serum-free medium triggers differentiation of a type I, neuron-lik