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Role of c-fos in hypoxia-induced AP-1 cis-element activity and tyrosine hydroxylase gene expression

โœ Scribed by Rangnath R. Mishra; Gautam Adhikary; Michael S. Simonson; Neil S. Cherniack; Nanduri R. Prabhakar


Book ID
117387156
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
897 KB
Volume
59
Category
Article
ISSN
0169-328X

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We have previously shown that the phorbol ester, TPA, which activates protein kinase C, causes, in PC12 cells, a transcriptional activation of tyrosine hydroxylase (TH), the key enzyme in catecholamine synthesis. The study has now been extended to examine the processes that underlie this transcripti