✦ LIBER ✦

Role of brain noradrenaline in morphine-induced stereotyped behaviour

✍ Scribed by I. H. Ayhan; A. Randrup

Publisher: Springer
Year: 1972
Tongue: English
Weight: 532 KB
Volume: 27
Category: Article
ISSN: 0033-3158
DOI: 10.1007/bf00422800

No coin nor oath required. For personal study only.

✦ Synopsis

The injections of morphine into rats which had been made tolerant to morphine produced stereotyped sniffing, licking and biting reminiscent of amphetamine-stereotypy. Pretreatment with drugs acting on the brain eatecholamines such as reserpine, H 44/68, FLA-63 and receptor blockers could inhibit this behaviour. Comparison between morphine and amphetamine stereotypy indicated that brain noradrenaline plays a more important role than dopamine in morphine induced stereotyped behaviour, in contrast to amphetamine stereotypy where dopamine is the most important brain amine. The result of experiments with intravcntricular injections of noradrenaline supported this conclusion, because the noradrenaline suppressed the blocking action of FLA-63 on morphine-induced stereotypy.

📜 SIMILAR VOLUMES

Propranolol-induced seizures in mice: th

Propranolol-induced seizures in mice: the role of noradrenaline

✍ G. J. Amabeoku; J. A. Syce 📂 Article 📅 1997 🏛 Springer 🌐 English ⚖ 134 KB

Effect of histidine on morphine-induced

Effect of histidine on morphine-induced changes in brain histamine

✍ R. W. Henwood; I. M. Mazurkiewicz-Kwilecki 📂 Article 📅 1977 🏛 SP Birkhäuser Verlag Basel 🌐 English ⚖ 521 KB

Effect of morphine on permeability of th

Effect of morphine on permeability of the blood-brain barrier in rats to noradrenalin-H3

✍ K. S. Raevskii; N. S. Tolmacheva 📂 Article 📅 1974 🏛 Springer US 🌐 English ⚖ 209 KB

The role of forebrain dopamine systems i

The role of forebrain dopamine systems in amphetamine induced stereotyped behavior in the rat

✍ Ian Creese; Susan D. Iversen 📂 Article 📅 1974 🏛 Springer 🌐 English ⚖ 733 KB

The caudate nucleus or the tuberculum olfactorium of the rat was lesioned by bilateral stereotaxic injection of 6-hydroxydopamine. The degree of dopamine depletion was assessed by a sensitive regional dopamine assay and revealed severe depletions in the lesioned areas. The locomotor response to a lo

On the role of noradrenaline in psychost

On the role of noradrenaline in psychostimulant-induced psychomotor activity and sensitization

✍ Louk J. M. J. Vanderschuren; Patricia Beemster; Anton N. M. Schoffelmeer 📂 Article 📅 2003 🏛 Springer 🌐 English ⚖ 303 KB

The effect of dopamine and noradrenaline

The effect of dopamine and noradrenaline blockade on amphetamine-induced behaviour in the marmoset

✍ P. R. Scraggs; R. M. Ridley 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 430 KB

Acute administration of 4 mg/kg damphetamine in the marmoset results in a large increase in small head movements (checking), an almost total suppression of purposeful activities and social interaction, but little change in the amount of locomotion. Checking behaviour is blocked in a dose dependent m