Viral and host factors in the pathogenes
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Cynthia A Derdeyn; Guido Silvestri
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Article
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2005
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Elsevier Science
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English
β 161 KB
Recent studies suggest that the pathogenesis of HIV infection and AIDS involves two distinct phases. During acute infection, massive depletion of CD4 + CCR5 + memory T cells within the mucosal-associated lymphoid tissue leads to major and potentially irreversible damage to CD4 + T-cell-mediated immu