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Role of Asp102 in the Catalytic Relay System of Serine Proteases: A Theoretical Study

✍ Scribed by Ishida, Toyokazu; Kato, Shigeki


Book ID
126023136
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
208 KB
Volume
126
Category
Article
ISSN
0002-7863

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Serine and cysteine proteases are structurally distinct families of proteolytic enzymes that exert analogous catalytic reactions. It is known that serine, histidine, and aspartate residues are involved in a putative catalytic triad of serine proteases whereas cysteine, histidine and aspartate (or as